The indication of cromosomal damage beside cromosomal aberation is micronucleus can preserve as indicator of dose absorbed.The probability occurrence of micronucleus higher than cromosomal aberation .micronucleus represent as cromosomal fragmen or whole chomosom that have not been incorporated in the main nuklei at cell division .the preparation and determine procedure had been done for cell culture limphocyte perifer for indentification micronuclei both konvensional method and cytokinesis blok with cytokhalasin B .The result swhowed that cytokinesis block method was more easier for identification on binucleat cell, furtheremore this method aplicable for dose respon curve micronulei. DRA.YANTI LUSIYANTI, DRA.IWIQ INDRAWATI, DRS.ABDUL WA'ID, MASNELLI LUBIS; Batan.
